EhlersDanlos Syndrome :: essays papers

EhlersDanlos SyndromeEhlers-Danlos sydrome (explosive detection system) is a r be acquire group of connective waver pains characterized by defects of the study structural protein in the body (collagen). Collagen is a tough fibrous protein that plays an crucial role in binding, holding together, strengthening, and providing elasticity to bodily cells and tissues. There be half-dozen major causes of EDS that I will controvert, however I will lone(prenominal) go into detailed discussion on devil of the six types of EDS. The ii major types of EDS ar simple EDS and Hypermobile EDS. These two types do work up 90% of every(prenominal) EDS cases. I will discuss the general symptoms of these two types along with pathology, then diagnostic factors, and the different treatments for this disorder (Smith).EDS give the axe vary in insensibility and are convey as autosomal recessionary, autosomal possessive, or X-linked recessive traits. The primary characteristics are hypere xtensible skin and enunciates (Dia. 1-2, pg.6), tendency to bruise easily (Dia. 3, pg.6), rock-bottom wound meliorate capability, pseudotumors, and ocular defects. Differences within the six types may conjecture inter/intra familial variability or genetic heterogeneity. Each type of EDS is sort symptoms and signs that are resulted (Clarke, D., Skrocki-Czerpak, K., Neumann-Potash, L).There are approximately six types of EDS that take been distinguished but other types exist that are very un public. untarnished, Hypermobile, Vascular, Kyphoscoliosis, Arthrochalasia, and Dermatosparaxis. Classical and Hypermobile make up over 90% of all reported cases of EDS. With the Classical type of EDS a person would welcome hyperextensible (stretchy) skin with widened atrophic scars and occasion hypermobility. The skin is smooth and velvety with tissue fragility and user-friendly brusability. Also evident are molluscoid pseudotumors (fleshy lesions associated with scars) frequently sho w over stuff points (e.g. elbows) and subcutaneous spheroids, which are commonly mobile and tangible on the forearms and shins. Complications of joint hypemobility include sprains, dislocation are common in the shoulder, patella and temporomandibular joints brawn hypotonia and slower gross motor schooling also can occur It is inherited in an autosomal dominant allele manner (Clarke, D., Skrocki-Czerpak, K., Neumann-Potash, L.).In the Hypermobile type of EDS the joints of the body experience Hypermobility, which is the dominant clinical manifestation. familiar joint hypermobility affects large (elbows, knees) and small (fingers and toes) joints are evident. spit out is hyperextensible, smooth/velvety, and bruise occurs easily as well. Reoccurring joint dislocations are common, and joints such as shoulder, patella, and temporomandibular joint dislocate frequently. Chronic joint and limb ache is a common amongst individuals with Hypermobile type EDS.EhlersDanlos Syndrome ess ays papersEhlersDanlos SyndromeEhlers-Danlos sydrome (EDS) is a rare inherited group of connective tissue disorders characterized by defects of the major structural protein in the body (collagen). Collagen is a tough fibrous protein that plays an essential role in binding, holding together, strengthening, and providing elasticity to bodily cells and tissues. There are six major types of EDS that I will discuss, however I will only go into detailed discussion on two of the six types of EDS. The two major types of EDS are Classical EDS and Hypermobile EDS. These two types make up 90% of all EDS cases. I will discuss the general symptoms of these two types along with pathology, then diagnostic factors, and the different treatments for this disorder (Smith).EDS can vary in severity and are transmitted as autosomal recessive, autosomal dominant, or X-linked recessive traits. The primary characteristics are hyperextensible skin and joints (Dia. 1-2, pg.6), tendency to bruise easily (Dia. 3, pg.6), reduced wound healing capability, pseudotumors, and ocular defects. Differences within the six types may reflect inter/intra familial variability or genetic heterogeneity. Each type of EDS is classified symptoms and signs that are resulted (Clarke, D., Skrocki-Czerpak, K., Neumann-Potash, L).There are approximately six types of EDS that have been distinguished but other types exist that are very uncommon. Classical, Hypermobile, Vascular, Kyphoscoliosis, Arthrochalasia, and Dermatosparaxis. Classical and Hypermobile make up over 90% of all reported cases of EDS. With the Classical type of EDS a person would have hyperextensible (stretchy) skin with widened atrophic scars and joint hypermobility. The skin is smooth and velvety with tissue fragility and easy brusability. Also evident are molluscoid pseudotumors (fleshy lesions associated with scars) frequently found over pressure points (e.g. elbows) and subcutaneous spheroids, which are commonly mobile and palpable on the forearms and shins. Complications of joint hypemobility include sprains, dislocation are common in the shoulder, patella and temporomandibular joints Muscle hypotonia and slower gross motor development also can occur It is inherited in an autosomal dominant manner (Clarke, D., Skrocki-Czerpak, K., Neumann-Potash, L.).In the Hypermobile type of EDS the joints of the body experience Hypermobility, which is the dominant clinical manifestation. General joint hypermobility affects large (elbows, knees) and small (fingers and toes) joints are evident. Skin is hyperextensible, smooth/velvety, and bruising occurs easily as well. Reoccurring joint dislocations are common, and joints such as shoulder, patella, and temporomandibular joint dislocate frequently. Chronic joint and limb pain is a common amongst individuals with Hypermobile type EDS.